Syno®C 引物合成
RNA合成
mRNA合成
Syno®GS 基因合成
载体构建
高通量及DNA文库构建
CRISPR基因编辑平台
病毒包装
基因测序及分析
重组蛋白表达平台
抗体工程平台
多肽服务
生物信息学分析与设计
CRISPR文库
ProXpress蛋白快速检测
CRISPR 质粒
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1
- Zhang Q, et al. Efficient DNA interrogation of SpCas9 governed by its electrostatic interaction with DNA beyond the PAM and protospacer. Nucleic Acids Res. 2021 Dec 2;49(21):12433-12444.
- doi: 10.1093/nar/gkab1139
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2
- Gao GB, Chen L, Pan JF, Lei T, Cai X, Hao Z, Wang Q, Shan G, Li J. LncRNA RGMB-AS1 inhibits HMOX1 ubiquitination and NAA10 activation to induce ferroptosis in non-small cell lung cancer. Cancer Lett. 2024.
- doi: 10.1016/j.canlet.2024.216826
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3
- Zhang P, Wang Z P, Sheng J, et al. High and efficient isomaltulose production using an engineered Yarrowia lipolytica strain[J]. Bioresource technology, 2018, 265: 577-580.
- doi:10.1016/j.biortech.2018.06.081
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4
- Liu, B., Kong, Q., Zhang, D., & Yan, L. (2018). Codon optimization significantly enhanced the expression of human 37-kDa iLRP in Escherichia coli. 3 Biotech,8(4).
- doi:10.1007/s13205-018-1234-y
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5
- Jin, W., Li, S., Chen, J., Liu, B., Li, J., Li, X., . . . Zhong, W. (2018). Increased soluble heterologous expression of a rat brain 3- O -sulfotransferase 1 – A key enzyme for heparin biosynthesis. Protein Expression and Purification,151, 23-29.
- doi:10.1016/j.pep.2018.06.007
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6
- Lei HQ, Wang ZF, Jiang DG, et al. CRISPR screening identififies CDK12 as a conservative vulnerability of prostate cancer. Cell Death Dis. 2021.
- doi: 10.1038/s41419-021-04027-6
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7
- Xu P, Liu ZH, Liu Y, et al. Genome-wide interrogation of gene functions through base editor screens empowered by barcoded sgRNAs. Nature Biotechnology. 2021.
- doi: 10.1038/s41587-021-00944-1
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8
- Zhu SY, Liu Y, Zhou Z, et al. Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry. 2021.
- doi: 10.1007/s11427-021-1990-5
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9
- Liu XJ, Liu TT, Shang YF, et al. ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells. Cell Reaserch. 2020.
- doi: 10.1038/s41422-020-0328-3
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10
- Chen A, Wen SJ, Liu F, et al. CRISPR/Cas9 screening identifies a kinetochore-microtubule dependent mechanism for Aurora-A inhibitor resistance in breast cancer. Cancer Communication. 2021.
- doi: 10.1002/cac2.12125
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11
- Bam Q, Yang P, Chou SJ, et al. Supramolecular Nanosubstrate-Mediated Delivery for CRISPR/Cas9 Gene Disruption and Deletion. Nano.micro.Small. 2021.
- doi: 10.1002/smll.202100546
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12
- Zhou J, Yin LJ, Dong YA, et al. CRISPR-Cas13a based bacterial detection platform: Sensing pathogen Staphylococcus aureus in food samples. Analytica Chimica Acta. 2020.
- doi: 10.1016/j.aca.2020.06.041
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